Controlling Coagulation in Blood with Red Light
نویسندگان
چکیده
Abstract Precise control of blood clotting and rapid reversal anticoagulation are essential in many clinical situations. We were successful modifying a thrombin‐binding aptamer with red‐light photocleavable linker derived from Cy7 by Cu‐catalyzed Click chemistry. able to show that we can successfully deactivate the modified red light (660 nm) even human blood—restoring blood's natural coagulation capability.
منابع مشابه
The Effect of Methylene Blue in Combination with Red Visible Light on Model Viruses Inactivation and Coagulation Factors in Fresh Frozen Plasma
Background and Aims: Fresh Frozen Plasma (FFP) is one of blood components. The risk of transmission of viruses from blood components regardless selection of blood donors and screening donated blood still remains. There are several methods for viral inactivation. In this study methylene blue (MB) photo inactivation process was used for inactivating viruses. Materials and Methods: In this study M...
متن کاملRed Blood Cells Using Phthalocyannes and Red Light
4,878,891 11/1989 Judy et al. .................................. 604/5 5,109,016 4/1992 Dixon et al. ..... ... 514/410 5,120,649 6/1992 Horowitz et al..... ... 435/173 5,232,844 8/1993 Horowitz et al. 435/173.1 5,238,940 8/1993 Liu et al. ......... ... 514/410 5,281,616 1/1994 Dixon et al. .. ... 514/410 5,407,808 4/1995 Halling et al. ... ... 435/34 5,484,778 1/1996 Kenney et al. .. ... 514/63...
متن کاملControlling spins with light.
The interaction of sub-picosecond laser pulses with magnetically ordered materials has developed into an extremely exciting research topic in modern magnetism. From the discovery of sub-picosecond demagnetization over a decade ago to the recent demonstration of magnetization reversal by a single 40 fs laser pulse, the manipulation of spins by ultrashort laser pulses has become a fundamentally c...
متن کاملLight scattering by multiple red blood cells.
The interaction of light with multiple red blood cells was systematically investigated by the finite-difference time-domain method (FDTD). The simulations showed that the lateral multiple scattering between red blood cells is very weak and that the polarization has an almost insignificant influence on the distribution of the scattered light. The numerical results of the FDTD method were compare...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2021
ISSN: ['1521-3773', '1433-7851', '0570-0833']
DOI: https://doi.org/10.1002/ange.202108468